Formulation and Evaluation of sustained release matrix tablets of Glipizide

formulation and evaluation of sustained release matrix tablets of glipizide

the purpose of this study was to develop a new monolithic matrix tablet to completely deliver glipizide in a zero order manner over a sustained period. two approaches were examined using drug in a formulation that contain polymer like hydroxylpropyl methyl-cellulose k 100 (hpmck) and eudragit l 100. the granules were prepared by wet granulation method and thereby formulated as f-1, f-2. f-3 and...

Formulation and Evaluation of Sustained Release Glipizide Matrix

Formulation and Evaluation of Sustained Release Matrix Tablets of Ranolazine

The aim of the present study was to prepare and characterize the Sustained release matrix tablets of Ranolazine using Kollidon® SR. Kollidon® SR is a polyvinyl acetate based excipient. Three different strengths i.e 375mg, 500mg and 750mg of ranolazine SR tablets were prepared by direct compression method and by using common blend. The influence of compression force was studied on the dissolutio...

Formulation and evaluation of sustained release matrix tablets of Isoniazid

Sustained release tablets of isoniazid were fabricated using guar gum and carbapol, Tragacanth Gum and PEG-6000, in different proportion and combinations by direct compression technique, Bulk density, tapped density, compressibility index, Hausner ratio before being punched as tablets. The tablets were evaluated for physical characteristic like hardness, weight variation, friability, and drug c...